PPIRE17995

Target Protein Information
Protein_Name Immunoglobulin heavy constant mu
Protein_Sequence SQSFPNVFPLVSCESPLSDKNLVAMGCLARDFLPSTISFTWNYQNNTEVIQGIRTFPTLRTGGKYLATSQVLLSPKSILEGSDEYLVCKIHYGGKNRDLHVPIPAVAEMNPNVNVFVPPRDGFSGPAPRKSKLICEATNFTPKPITVSWLKDGKLVESGFTTDPVTIENKGSTPQTYKVISTLTISEIDWLNLNVYTCRVDHRGLTFLKNVSSTCAASPSTDILTFTIPPSFADIFLSKSANLTCLVSNLATYETLNISWASQSGEPLETKIKIMESHPNGTFSAKGVASVCVEDWNNRKEFVCTVTHRDLPSPQKKFISKPNEVHKHPPAVYLLPPAREQLNLRESATVTCLVKGFSPADISVQWLQRGQLLPQEKYVTSAPMPEPGAPGFYFTHSILTVTEEEWNSGETYTCVVGHEALPHLVTERTVDKSTGKPTLYNVSLIMSDTGGTCY
Organism_Source Mus musculus
Functional_Classification immunoglobulins
Cellular_Localization Extracellular
Gene_Names Ighm
UniProt_ID P01872
Protein-Protein Interaction Networks
Peptide Basic Information
Peptide_Name ADGADRPVPYGACG(Orn-biotin)
Peptide_Sequence ADGADRPVPYGACGX
Peptide_Length 15
Peptide_SMILES CC(C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CS)C(=O)NCC(=O)NCC(=O)O
Chemical_Modification X16=Orn-biotin
Cyclization_Method None
Linear/Cyclic Linear
N-terminal_Modification Free
C-terminal_Modification Free
Amino_Acid_Distribution
Peptide Physicochemical
Molecular_Weight 1405.50
Aliphatic_Index 39.33333
Aromaticity 0.06667
Average_Rotatable_Bonds 2.60000
Charge_at_pH_7 -1.06395
Isoelectric_Point 4.10922
Number_of_Hydrogen_Bond_Acceptors 21
Number_of_Hydrogen_Bond_Donors 21
Topological_Polar_Surface_Area 609.87000
X_logP_energy -8.47003
Interaction Information
Affinity KD=625 nM
Affinity_Assay Microscale Thermophoresis
PDB_ID None
Type Affinity ligand
Structure
Reference Information
Document_Type Research Articles
Title NMR Studies of the Antibody-Bound Conformation of a Carbohydrate-Mimetic Peptide
Release_Year 2002
PMID 11841205
DOI 10.1021/bi011927u