PPIPT02444
Target Protein Information
| Protein_Name | Oplophorus-luciferin 2-monooxygenase catalytic subunit |
|---|---|
| Protein_Sequence | MAYSTLFIIALTAVVTQASSTQKSNLTFTLADFVGDWQQTAGYNQDQVLEQGGLSSLFQALGVSVTPIQKVVLSGENGLKADIHVIIPYEGLSGFQMGLIEMIFKVVYPVDDHHFKIILHYGTLVIDGVTPNMIDYFGRPYPGIAVFDGKQITVTGTLWNGNKIYDERLINPDGSLLFRVTINGVTGWRLCENILA |
| Organism_Source | Other organisms |
| Functional_Classification | Oxidoreductase (monooxygenase) |
| Cellular_Localization | Extracellular |
| Gene_Names | |
| UniProt_ID | Q9GV45 |
| Protein-Protein Interaction Networks | |
Peptide Basic Information
| Peptide_Name | SmTrip10 |
|---|---|
| Peptide_Sequence | SSWKRGSMLFRVTINSVS |
| Peptide_Length | 18 |
| Peptide_SMILES | CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CO)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)O)C(C)C |
| Chemical_Modification | None |
| Cyclization_Method | none |
| Linear/Cyclic | Linear |
| N-terminal_Modification | free |
| C-terminal_Modification | free |
| Amino_Acid_Distribution | |
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Peptide Physicochemical
| Molecular_Weight | 2055.38 |
|---|---|
| Aliphatic_Index | 75.55556 |
| Aromaticity | 0.11111 |
| Average_Rotatable_Bonds | 3.77778 |
| Charge_at_pH_7 | 2.99768 |
| Isoelectric_point | 12.51648 |
|---|---|
| Number_of_Hydrogen_Bond_Acceptors | 30 |
| Number_of_Hydrogen_Bond_Donors | 34 |
| Topological_Polar_Surface_Area | 888.10000 |
| X_logP_energy | -10.73146 |
Interaction Information
| Affinity | KD=0.10 uM |
|---|---|
| Affinity_Assay | luminescence complementation assay |
| PDB_ID | None |
| Type | Affinity ligand |
| Structure | |
Reference Information
| Document_Type | Patent |
|---|---|
| Title | MULTIPARTITE LUCIFERASE PEPTIDES AND POLYPEPTIDES |
| Release_Year | 2021 |
| Patent_ID | US20210262941A1 |