PPIST00730

Protein Information
Protein_Chain A
Protein_Sequence DCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFG
Peptide Information
Peptide_Chain B
Peptide_Sequence DFEEIPEAYLA
Peptide_Length 11
Non-standard residues No
Interaction Information
PDB_ID 1TA6
Method X-RAY DIFFRACTION
Resolution 1.90 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Design and synthesis of a series of potent and orally bioavailablenoncovalent thrombin inhibitors that utilize nonbasic groups in the P1 position
Release_Year 1998
PMID 9703466
DOI 10.1021/jm9801713