PPIST01539

Protein Information
Protein_Chain A[auth L]/B[auth H]
Protein_Sequence TFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGR/IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE
Peptide Information
Peptide_Chain C[auth I]
Peptide_Sequence GDFEEIPEEYLQ
Peptide_Length 12
Non-standard residues No
Interaction Information
PDB_ID 3TU7
Method X-RAY DIFFRACTION
Resolution 2.49 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Molecular design and structure-activity relationships leading to the potent, selective, and orally active thrombin active site inhibitor BMS-189664.
Release_Year 2002
PMID None
DOI None