PPIST01619

Protein Information
Protein_Chain A/B
Protein_Sequence TFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGR/IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE
Peptide Information
Peptide_Chain C
Peptide_Sequence DFEEIPEEYLQ
Peptide_Length 11
Non-standard residues No
Interaction Information
PDB_ID 1MU6
Method X-RAY DIFFRACTION
Resolution 1.99 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines.
Release_Year 2003
PMID 12570369
DOI 10.1021/jm020311f