PPIST01816

Protein Information
Protein_Chain A;B
Protein_Sequence MASMTGGQQMGAPITAYAQQTRGLLGCIITSLTGRDKNQVEGEVQIVSTATQTFLATCINGVCWTVYHGAGTRTIASPKGPVIQMYTNVDQDLVGWPAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGLFRAAVCTRGVTKAVDFIPVENLETTMRSGSHHHHHH
Peptide Information
Peptide_Chain C;D
Peptide_Sequence KKGSVVIVGRIVLSGKPAIIPKK
Peptide_Length 23
Non-standard residues No
Interaction Information
PDB_ID 1RTL
Method X-RAY DIFFRACTION
Resolution 2.75 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Pyrrolidine-5,5-trans-lactams. 4. Incorporation of a P3/P4 urea leads to potent intracellular inhibitors of hepatitis C virus NS3/4A protease
Release_Year 2003
PMID 14627400
DOI 10.1021/ol035826v