PPIST01974

Protein Information
Protein_Chain A
Protein_Sequence DCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFG
Peptide Information
Peptide_Chain B
Peptide_Sequence DFEEIPEEYLA
Peptide_Length 11
Non-standard residues No
Interaction Information
PDB_ID 1SL3
Method X-RAY DIFFRACTION
Resolution 1.81 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Discovery and evaluation of potent P1 aryl heterocycle-based thrombin inhibitors
Release_Year 2004
PMID 15163182
DOI 10.1021/jm030303e