PPIST02068

Protein Information
Protein_Chain B;D
Protein_Sequence IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGAGCDRDGKYGFYTHVFRLKKWIQKVIDQF
Peptide Information
Peptide_Chain A;C
Peptide_Sequence EADCGLRPLFEKKSLEDKTERELLESYIDGR
Peptide_Length 31
Non-standard residues No
Interaction Information
PDB_ID 1TQ0
Method X-RAY DIFFRACTION
Resolution 2.80 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket
Release_Year 2004
PMID 15252033
DOI 10.1074/jbc.M407272200