PPIST02077

Protein Information
Protein_Chain A/B
Protein_Sequence ADCGLRPLFEKKSLEDKTERELLESYID/IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCARKGKYGFYTHVFRLKKWIQKVIDQFGE
Peptide Information
Peptide_Chain C
Peptide_Sequence DFEEIPGEYL
Peptide_Length 10
Non-standard residues No
Interaction Information
PDB_ID 1TWX
Method X-RAY DIFFRACTION
Resolution 2.40 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Crystal structure of the thrombin mutant D221A/D222K: the Asp222:Arg187 ion-pair stabilizes the fast form
Release_Year 2004
PMID 15572256
DOI 10.1016/j.bpc.2004.07.027