PPIST02191

Protein Information
Protein_Chain A[auth M]
Protein_Sequence GSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSEN
Peptide Information
Peptide_Chain B[auth P]
Peptide_Sequence RFMDYWEGL
Peptide_Length 9
Non-standard residues No
Interaction Information
PDB_ID 1T4F
Method X-RAY DIFFRACTION
Resolution 1.90 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells
Release_Year 2005
PMID 15715460
DOI 10.1021/jm049137g