PPIST02995

Protein Information
Protein_Chain A;B
Protein_Sequence MGSSHHHHHHSSGEVPRGSHMLETEEEEEEGAGATLSRGPAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGDDPWTEHAKWFPGCQFLLRSKGQEYINNIHLTHSL
Peptide Information
Peptide_Chain C;D
Peptide_Sequence AVPW
Peptide_Length 4
Non-standard residues No
Interaction Information
PDB_ID 2I3H
Method X-RAY DIFFRACTION
Resolution 1.62 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs.
Release_Year 2006
PMID 17168540
DOI 10.1021/cb600276q