PPIST04342

Protein Information
Protein_Chain A;B;BA[auth E];CA[auth F];D[auth I];EA[auth M];E[auth J];FA[auth N];G[auth Q];HA[auth U];H[auth R];IA[auth V];J[auth Y];K[auth Z];M[auth c];N[auth d];P[auth g];Q[auth h];S[auth k];T[auth l];V[auth o];W[auth p];Y[auth s];Z[auth t]
Protein_Sequence MVLEKIEPAQEEHEKYHSNVKELSHKFGIPNLVARQIVNSCAQCQQKGEAIHGQVNAELGTWQMDCTHLEGKIIIVAVHVASGFIEAEVIPQESGRQTALFLLKLASRWPITHLHTDNGANFTSQEVKMVAWWIGIEQSFGVPYNPQSQGVVEAMNHHLKNQISRIREQANTIETIVLMAVHCMNFKRRGGIGDMTPSERLINMITTEQE
Peptide Information
Peptide_Chain AA[auth C];C[auth G];DA[auth K];F[auth O];GA[auth S];I[auth W];JA[auth a];L[auth e];O[auth i];R[auth m];U[auth q];X[auth u]
Peptide_Sequence SMDSRLQRIHAEIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNMFLVGEGDSVLEVLFQ
Peptide_Length 95
Non-standard residues No
Interaction Information
PDB_ID 3F9K
Method X-RAY DIFFRACTION
Resolution 3.20 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75
Release_Year 2009
PMID 19132083
DOI 10.1371/journal.ppat.1000259