PPIST05025

Protein Information
Protein_Chain A;C
Protein_Sequence MASMTGGQQMGAPITAYAQQTRGLLGCIITSLTGRDKNQVEGEVQIVSTATQTFLATCINGVCWTVYHGAGTRTIASPKGPVIQMYTNVDQDLVGWPAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGLFRAAVCTRGVAKAVDFIPVENLETTMRSGSHHHHHH
Peptide Information
Peptide_Chain B;D
Peptide_Sequence KKGSVVIVGRIVLSGKPAIIPKK
Peptide_Length 23
Non-standard residues No
Interaction Information
PDB_ID 3LOX
Method X-RAY DIFFRACTION
Resolution 2.65 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir: a change in direction in the search for a second generation HCV NS3 protease inhibitor.
Release_Year 2010
PMID 20303756
DOI 10.1016/j.bmcl.2010.02.063