PPIST05204

Protein Information
Protein_Chain A
Protein_Sequence GSHMELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEAFSAEENFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEARIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ
Peptide Information
Peptide_Chain B
Peptide_Sequence KDHQLLRYLLDKDE
Peptide_Length 14
Non-standard residues No
Interaction Information
PDB_ID 3OKH
Method X-RAY DIFFRACTION
Resolution 2.50 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetes
Release_Year 2010
PMID 21134747
DOI 10.1016/j.bmcl.2010.11.039