PPIST05560

Protein Information
Protein_Chain A
Protein_Sequence IVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDAGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAANS
Peptide Information
Peptide_Chain B[auth E]
Peptide_Sequence RPDFCLEPPYTGPCRADIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCGGA
Peptide_Length 58
Non-standard residues No
Interaction Information
PDB_ID 3P95
Method X-RAY DIFFRACTION
Resolution 1.30 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title The P2' residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activity.
Release_Year 2011
PMID 21806544
DOI 10.1042/BJ20110788