PPIST06111

Protein Information
Protein_Chain A[auth L]/B[auth H]
Protein_Sequence TFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGR/IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE
Peptide Information
Peptide_Chain C[auth I]
Peptide_Sequence NGDFEEIPEEYLQ
Peptide_Length 13
Non-standard residues No
Interaction Information
PDB_ID 3T5F
Method X-RAY DIFFRACTION
Resolution 1.45 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Ligand binding stepwise disrupts water network in thrombin: enthalpic and entropic changes reveal classical hydrophobic effect
Release_Year 2012
PMID 22612268
DOI 10.1021/jm300337q