PPIST07158

Protein Information
Protein_Chain A;B
Protein_Sequence GDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGG
Peptide Information
Peptide_Chain C;D
Peptide_Sequence XALETLRRVGDGVQRNHX
Peptide_Length 18
Non-standard residues Yes
Interaction Information
PDB_ID 4HW4
Method X-RAY DIFFRACTION
Resolution 1.53 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Discovery of potent myeloid cell leukemia 1 (Mcl-1) inhibitors using fragment-based methods and structure-based design.
Release_Year 2013
PMID 23244564
DOI 10.1021/jm301448p