PPIST07397

Protein Information
Protein_Chain A;C[auth B]
Protein_Sequence MHHHHHHSSGVDLGTENLYFQSMLNTSGSGTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAM
Peptide Information
Peptide_Chain B[auth C];D
Peptide_Sequence KMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPEG
Peptide_Length 49
Non-standard residues No
Interaction Information
PDB_ID 4L31
Method X-RAY DIFFRACTION
Resolution 2.00 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity.
Release_Year 2013
PMID 24116873
DOI 10.1021/jm401463y