PPIST07467

Protein Information
Protein_Chain A
Protein_Sequence LPGEGTQVHPRAPLLQILKVAGAQEEVFTVKEVMHYLGQYIMMKQLYDKQRQHIVHCHDDPLGELLEVGSFSVKNPSPLYEMLKRNLVIL
Peptide Information
Peptide_Chain B
Peptide_Sequence XLTFXEYWAQXLSAA
Peptide_Length 15
Non-standard residues Yes
Interaction Information
PDB_ID 4N5T
Method X-RAY DIFFRACTION
Resolution 1.70 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Stapled alpha-helical peptide drug development: a potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy.
Release_Year 2013
PMID 23946421
DOI 10.1073/pnas.1303002110