PPIST07729

Protein Information
Protein_Chain A;C
Protein_Sequence GSMAPITAYSQQTRGLLGCIITSLTGRDKNQVDGEVQVLSTATQSFLATCVNGVCWTVYHGAGSKTLAGPKGPITQMYTNVDQDLVGWPAPPGARSMTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPVSYLKGSSGGPLLCPSGHVVGIFRAAVCTRGVAKAVDFIPVESMETTMRSPVFTDN
Peptide Information
Peptide_Chain B;D
Peptide_Sequence KGSVVIVGRIILSGRK
Peptide_Length 16
Non-standard residues No
Interaction Information
PDB_ID 4KTC
Method X-RAY DIFFRACTION
Resolution 2.30 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Discovery of Danoprevir (ITMN-191/R7227), a Highly Selective and Potent Inhibitor of Hepatitis C Virus (HCV) NS3/4A Protease.
Release_Year 2014
PMID 23672640
DOI 10.1021/jm400164c