PPIST08573

Protein Information
Protein_Chain A;C[auth D]
Protein_Sequence MHHHHHHGENLYFQGSAPYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFSTE
Peptide Information
Peptide_Chain B;D[auth E]
Peptide_Sequence AHKILHRLLQE
Peptide_Length 11
Non-standard residues No
Interaction Information
PDB_ID 4WPF
Method X-RAY DIFFRACTION
Resolution 2.20 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Minor Structural Change to Tertiary Sulfonamide RORc Ligands Led to Opposite Mechanisms of Action.
Release_Year 2015
PMID 25815138
DOI 10.1021/ml500420y