PPIST08587

Protein Information
Protein_Chain A;B
Protein_Sequence MGSSHHHHHHSSGETVRFQGHMRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFACGGKLKNWEPGDRAWSEHRRHFPNCFFVL
Peptide Information
Peptide_Chain C;D
Peptide_Sequence AFPFFX
Peptide_Length 6
Non-standard residues Yes
Interaction Information
PDB_ID 4WVT
Method X-RAY DIFFRACTION
Resolution 1.96 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title The Discovery of Macrocyclic XIAP Antagonists from a DNA-Programmed Chemistry Library, and Their Optimization To Give Lead Compounds with in Vivo Antitumor Activity.
Release_Year 2015
PMID 25695766
DOI 10.1021/jm501892g