PPIST08619

Protein Information
Protein_Chain A
Protein_Sequence IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVGYGDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQAVHHHHHH
Peptide Information
Peptide_Chain B[auth H]
Peptide_Sequence MDDDDKMDNECTTKIKPR
Peptide_Length 18
Non-standard residues No
Interaction Information
PDB_ID 4X6N
Method X-RAY DIFFRACTION
Resolution 2.10 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties.
Release_Year 2015
PMID 25728130
DOI 10.1016/j.bmcl.2015.01.028