PPIST09061

Protein Information
Protein_Chain C[auth L]/A[auth H]
Protein_Sequence EADCGLRPLFEKKSLEDKTERELLESYID/IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFG
Peptide Information
Peptide_Chain B[auth I]
Peptide_Sequence GDFEEIPEEYLQ
Peptide_Length 12
Non-standard residues No
Interaction Information
PDB_ID 4UFE
Method X-RAY DIFFRACTION
Resolution 1.59 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Boosting Affinity by Correct Ligand Preorganization for the S2 Pocket of Thrombin: A Study by Isothermal Titration Calorimetry, Molecular Dynamics, and High-Resolution Crystal Structures.
Release_Year 2016
PMID 26762840
DOI 10.1002/CMDC.201500531