PPIST09278

Protein Information
Protein_Chain A;B;D[auth E];E[auth F];G[auth I];H[auth J]
Protein_Sequence MGSMVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQ
Peptide Information
Peptide_Chain C;F[auth G];I[auth K]
Peptide_Sequence QARRRQSVLNLMTHSVNQGQNIHRKTTASTRKVSLAPQAN
Peptide_Length 40
Non-standard residues No
Interaction Information
PDB_ID 5D3E
Method X-RAY DIFFRACTION
Resolution 2.75 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR.
Release_Year 2016
PMID 26888287
DOI 10.1073/pnas.1516631113