PPIST09510

Protein Information
Protein_Chain A
Protein_Sequence MGSSHHHHHHSSGLVPRGSHMAALRERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVFALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
Peptide Information
Peptide_Chain B
Peptide_Sequence XVRMA
Peptide_Length 5
Non-standard residues Yes
Interaction Information
PDB_ID 5F5J
Method X-RAY DIFFRACTION
Resolution 2.40 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis.
Release_Year 2016
PMID 26805573
DOI 10.1016/j.molcel.2015.12.022