PPIST10428

Protein Information
Protein_Chain A[auth B];B[auth C];C[auth E]
Protein_Sequence AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAAYA
Peptide Information
Peptide_Chain D[auth A];E[auth D];F
Peptide_Sequence FANPHLSWSWXXRCGX
Peptide_Length 16
Non-standard residues Yes
Interaction Information
PDB_ID 5O4Y
Method X-RAY DIFFRACTION
Resolution 2.30 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Bioactive Macrocyclic Inhibitors of the PD-1/PD-L1 Immune Checkpoint.
Release_Year 2017
PMID 28881104
DOI 10.1002/anie.201707707