PPIST10586

Protein Information
Protein_Chain A;B;C;D
Protein_Sequence GSPASGTSLSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL
Peptide Information
Peptide_Chain E[auth L];F[auth M];G[auth N];H[auth P]
Peptide_Sequence KFEGXDNEX
Peptide_Length 9
Non-standard residues Yes
Interaction Information
PDB_ID 5TYI
Method X-RAY DIFFRACTION
Resolution 2.15 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Discovery, Development, and Cellular Delivery of Potent and Selective Bicyclic Peptide Inhibitors of Grb7 Cancer Target.
Release_Year 2017
PMID 29083893
DOI 10.1021/acs.jmedchem.7b01320