PPIST10644

Protein Information
Protein_Chain A;B
Protein_Sequence GSDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLE
Peptide Information
Peptide_Chain C;D
Peptide_Sequence XQWVREIAAGLRRAADDVNAQVERX
Peptide_Length 25
Non-standard residues Yes
Interaction Information
PDB_ID 5UUM
Method X-RAY DIFFRACTION
Resolution 2.35 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1.
Release_Year 2017
PMID 28594323
DOI 10.7554/eLife.25541