PPIST10668

Protein Information
Protein_Chain A
Protein_Sequence GPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
Peptide Information
Peptide_Chain B[auth I]
Peptide_Sequence KGTAQLKPIESSILAQRRVRK
Peptide_Length 21
Non-standard residues No
Interaction Information
PDB_ID 5V62
Method X-RAY DIFFRACTION
Resolution 1.90 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors.
Release_Year 2017
PMID 28740606
DOI 10.1021/acsmedchemlett.7b00127