PPIST11193

Protein Information
Protein_Chain A;C[auth B];D[auth C];F[auth D]
Protein_Sequence EPDIRPCGRSLVIISTLDGRIAALDPENHGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGDLFQWDRDRESMETVPFTVESLLESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDNDEMEQEEDILLLQRTQKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTLKPSGNKEQSKIISDVEEQEAVMMDTVIKVSVADWKVMAFNKKGGHLEWEYQFSTPIASAWLVKDGKVIPISLFDDTSYAPNDGVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPTSPKALESVSSE
Peptide Information
Peptide_Chain B[auth E];E[auth F];G
Peptide_Sequence ADPQPWRFYAPR
Peptide_Length 12
Non-standard residues No
Interaction Information
PDB_ID 5V1D
Method X-RAY DIFFRACTION
Resolution 2.80 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title The luminal domain of the ER stress sensor protein PERK binds misfolded proteins and thereby triggers PERK oligomerization
Release_Year 2018
PMID 29386355
DOI 10.1074/jbc.RA117.001294