PPIST11231

Protein Information
Protein_Chain A
Protein_Sequence GDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFH
Peptide Information
Peptide_Chain B
Peptide_Sequence IWLLQSLLRLGDEINAYYARRX
Peptide_Length 22
Non-standard residues Yes
Interaction Information
PDB_ID 5W8F
Method X-RAY DIFFRACTION
Resolution 1.85 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells.
Release_Year 2018
PMID 29339518
DOI 10.1073/pnas.1712952115