PPIST11543

Protein Information
Protein_Chain A;B;C;D
Protein_Sequence IISRNFPIIGVKEKTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIDGANRTDICQGELGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRNMDNSLLQDSDLDPRGSDERPTRTIIPVQYETRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLTADLEHHHHHH
Peptide Information
Peptide_Chain E[auth F];F[auth G];G[auth H];H[auth I]
Peptide_Sequence XLLR
Peptide_Length 4
Non-standard residues Yes
Interaction Information
PDB_ID 6BKJ
Method X-RAY DIFFRACTION
Resolution 3.20 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Structures of human calpain-3 protease core with and without bound inhibitor reveal mechanisms of calpain activation.
Release_Year 2018
PMID 29382717
DOI 10.1074/jbc.RA117.001097