PPIST11612

Protein Information
Protein_Chain A;B
Protein_Sequence GSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLS
Peptide Information
Peptide_Chain C;D
Peptide_Sequence GTYEDLVQAQKEITAHNMQLREQTKQLEHDMAELRDQSQLLLKARCEELK
Peptide_Length 50
Non-standard residues No
Interaction Information
PDB_ID 6CKO
Method X-RAY DIFFRACTION
Resolution 2.00 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Structural and functional analysis of the DOT1L-AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis.
Release_Year 2018
PMID 29563185
DOI 10.1101/gad.311639.118