PPIST11824

Protein Information
Protein_Chain A;B
Protein_Sequence GPYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLSKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFSTETESPVGLSK
Peptide Information
Peptide_Chain C[auth P];D[auth Q]
Peptide_Sequence NSHQKVTLLQLLLGHKNEEN
Peptide_Length 20
Non-standard residues No
Interaction Information
PDB_ID 6FZU
Method X-RAY DIFFRACTION
Resolution 1.80 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Optimizing a Weakly Binding Fragment into a Potent ROR gamma t Inverse Agonist with Efficacy in an in Vivo Inflammation Model.
Release_Year 2018
PMID 29990434
DOI 10.1021/acs.jmedchem.8b00529