PPIST12025

Protein Information
Protein_Chain B[auth L]; E[auth M]/C[auth H]; F[auth I]
Protein_Sequence DILDIQMTQSPASLSASVGETVTITCGASENIYGALTWYQRKQGKSPQLLIYGAINLADDKSSRFSGSGSGRQYSLKISSLHPDDVATYYCQNVLSTPFTFGSGTKLEIKAA/EVQLVESGGGVVQPGGSLKLSCAASGFTFSTYDMSWVRQTPDKRLELVATINSNGGSTYYPDSVKGRFTSSRDNAKNILYLQMSSLKSEDTAMYYCAREALLRPAYYALDYWGQGTSVTVSSAGGGGSGGGGSGGGGS
Peptide Information
Peptide_Chain A; D[auth B]
Peptide_Sequence MGPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ
Peptide_Length 91
Non-standard residues No
Interaction Information
PDB_ID 6A79
Method X-RAY DIFFRACTION
Resolution 2.31 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface.
Release_Year 2019
PMID 30595454
DOI 10.1016/j.str.2018.11.002