PPIST12228

Protein Information
Protein_Chain A;C[auth H]
Protein_Sequence IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE
Peptide Information
Peptide_Chain B;D[auth L]
Peptide_Sequence TFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGR
Peptide_Length 36
Non-standard residues No
Interaction Information
PDB_ID 6GWE
Method X-RAY DIFFRACTION
Resolution 2.30 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Thiol-to-amine cyclization reaction enables screening of large libraries of macrocyclic compounds and the generation of sub-kilodalton ligands.
Release_Year 2019
PMID 31457083
DOI 10.1126/sciadv.aaw2851