PPIST12272

Protein Information
Protein_Chain A;B
Protein_Sequence SKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARI
Peptide Information
Peptide_Chain C[auth N]
Peptide_Sequence GSHGHHHHH
Peptide_Length 9
Non-standard residues No
Interaction Information
PDB_ID 6HK4
Method X-RAY DIFFRACTION
Resolution 2.50 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Investigating Drug-Target Residence Time in Kinases through Enhanced Sampling Simulations.
Release_Year 2019
PMID 31246463
DOI 10.1021/acs.jctc.9b00104