PPIST12441

Protein Information
Protein_Chain A
Protein_Sequence MGSSHHHHHHSQDPDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPF
Peptide Information
Peptide_Chain B
Peptide_Sequence MHSPNPLLVAPTPPALQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQQK
Peptide_Length 82
Non-standard residues No
Interaction Information
PDB_ID 6JN2
Method X-RAY DIFFRACTION
Resolution 3.60 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title A higher-order configuration of the heterodimeric DOT1L-AF10 coiled-coil domains potentiates their leukemogenenic activity.
Release_Year 2019
PMID 31527241
DOI 10.1073/pnas.1904672116