PPIST12729

Protein Information
Protein_Chain A;B
Protein_Sequence GPRSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQSSPSYSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTNIEDEGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE
Peptide Information
Peptide_Chain C;D
Peptide_Sequence XPWRLRKXPDSFAKEPX
Peptide_Length 17
Non-standard residues Yes
Interaction Information
PDB_ID 6Q36
Method X-RAY DIFFRACTION
Resolution 2.01 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Structure-based design of potent linear peptide inhibitors of the YAP-TEAD protein-protein interaction derived from the YAP omega-loop sequence.
Release_Year 2019
PMID 31235263
DOI 10.1016/j.bmcl.2019.06.022