PPIST12885

Protein Information
Protein_Chain A;B
Protein_Sequence GSMSEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVL
Peptide Information
Peptide_Chain C;D[auth F]
Peptide_Sequence XXPPXTEDEL
Peptide_Length 10
Non-standard residues Yes
Interaction Information
PDB_ID 5ND0
Method X-RAY DIFFRACTION
Resolution 1.45 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Release_Year 2020
PMID 33184177
DOI 10.1073/pnas.2007213117