PPIST13828

Protein Information
Protein_Chain A[auth L]/B[auth H]
Protein_Sequence EADCGLRPLFEKKSLEDKTERELLESYID/IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFG
Peptide Information
Peptide_Chain C[auth I]
Peptide_Sequence GDFEEIPEEYL
Peptide_Length 11
Non-standard residues No
Interaction Information
PDB_ID 6ZUG
Method X-RAY DIFFRACTION
Resolution 1.80 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Design, Synthesis, and Pharmacological Characterization of a Neutral, Non-Prodrug Thrombin Inhibitor with Good Oral Pharmacokinetics.
Release_Year 2020
PMID 33108181
DOI 10.1021/acs.jmedchem.0c01035