PPIST14571

Protein Information
Protein_Chain A;B
Protein_Sequence GPGSEFVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSG
Peptide Information
Peptide_Chain C;D
Peptide_Sequence XRIRRDEYLKAIQX
Peptide_Length 14
Non-standard residues Yes
Interaction Information
PDB_ID 7F7G
Method X-RAY DIFFRACTION
Resolution 2.45 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Entropy of stapled peptide inhibitors in free state is the major contributor to the improvement of binding affinity with the GK domain.
Release_Year 2021
PMID 34458841
DOI 10.1039/d1cb00087j