PPIST14825

Protein Information
Protein_Chain A;B
Protein_Sequence SMNSLALSLTADQIISALLEAEPPILYSEYDPSRPFSEAYMMGLLTNLADRELVHMINWAKKVPGFVDLSLHDQVHLLESAWLEILMIGLVWRSMDHPGKLLFAPDLLLDREQGKSVEGMVEIFDMLLATSERFREMKLQREEFVCLKAIILLNSGVYTFLSSTLKSLENKEKIHRMLDKITDALIWYMAKSGLSLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKSKNVVPLSDLLLEMLDAHR
Peptide Information
Peptide_Chain C;D
Peptide_Sequence XKHKILHRLLQDSSS
Peptide_Length 15
Non-standard residues Yes
Interaction Information
PDB_ID 7NEL
Method X-RAY DIFFRACTION
Resolution 1.45 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title A PROSS-designed extensively mutated estrogen receptor alpha variant displays enhanced thermal stability while retaining native allosteric regulation and structure.
Release_Year 2021
PMID 34006920
DOI 10.1038/s41598-021-89785-1