PPIST14997

Protein Information
Protein_Chain A;B
Protein_Sequence AMTEYKLVVVGADGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKKSKTKCVIM
Peptide Information
Peptide_Chain C[auth E];D[auth F]
Peptide_Sequence AXPLYISYDPVCRA
Peptide_Length 14
Non-standard residues Yes
Interaction Information
PDB_ID 7ROV
Method X-RAY DIFFRACTION
Resolution 1.32 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling.
Release_Year 2021
PMID 35024121
DOI 10.1039/d1sc05187c