PPIST15260

Protein Information
Protein_Chain A[auth AAA]; C[auth CCC]/B[auth BBB]; D[auth DDD]
Protein_Sequence KEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLREFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAS/GDTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTVYPAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTSPLTVEWRAR
Peptide Information
Peptide_Chain E[auth EEE]; F[auth FFF]
Peptide_Sequence GIAGFKGEQGPKGEP
Peptide_Length 15
Non-standard residues No
Interaction Information
PDB_ID 7NZE
Method X-RAY DIFFRACTION
Resolution 2.05 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Key interactions in the trimolecular complex consisting of the rheumatoid arthritis-associated DRB1*04:01 molecule, the major glycosylated collagen II peptide and the T-cell receptor.
Release_Year 2022
PMID 35027402
DOI 10.1136/annrheumdis-2021-220500