PPIST15605

Protein Information
Protein_Chain B;D
Protein_Sequence SVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
Peptide Information
Peptide_Chain A;C
Peptide_Sequence ECGWRIGEAGTDPNLNHQQFRAKILSIWEECX
Peptide_Length 32
Non-standard residues Yes
Interaction Information
PDB_ID 7TA3
Method X-RAY DIFFRACTION
Resolution 2.50 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Trimer-to-Monomer Disruption Mechanism for a Potent, Protease-Resistant Antagonist of Tumor Necrosis Factor-alpha Signaling.
Release_Year 2022
PMID 35613436
DOI 10.1021/jacs.1c13717