PPIST15816

Protein Information
Protein_Chain A;C
Protein_Sequence GSHMDNQCTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFWLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFTYDLFLNLEGNPPVNHLNHLRCEKLTFNNPTTEFRYKLLRAGGVMVMPEGAHHHHHH
Peptide Information
Peptide_Chain B;D
Peptide_Sequence AARK
Peptide_Length 4
Non-standard residues No
Interaction Information
PDB_ID 7X8B
Method X-RAY DIFFRACTION
Resolution 2.30 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer.
Release_Year 2022
PMID 36272410
DOI 10.1016/j.molcel.2022.09.034