PPIST15821

Protein Information
Protein_Chain A;B;C
Protein_Sequence MYNFFPRKPKWDKNQITYRIIGYTPDLAPETVDDAFARAFQVWSDVTPLRFSRIYDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGKGVGYSLFLVAAHAFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPD
Peptide Information
Peptide_Chain D;E;F
Peptide_Sequence XNDALIXX
Peptide_Length 8
Non-standard residues Yes
Interaction Information
PDB_ID 7XGJ
Method X-RAY DIFFRACTION
Resolution 2.80 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Discovery of Aryloxyphenyl-Heptapeptide Hybrids as Potent and Selective Matrix Metalloproteinase-2 Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis.
Release_Year 2022
PMID 35687819
DOI 10.1021/acs.jmedchem.2c00613