PPIST15844

Protein Information
Protein_Chain A;B
Protein_Sequence PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
Peptide Information
Peptide_Chain C
Peptide_Sequence FVPVLWLFX
Peptide_Length 9
Non-standard residues Yes
Interaction Information
PDB_ID 7YF6
Method X-RAY DIFFRACTION
Resolution 2.01 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Highly Potent and Oral Macrocyclic Peptides as a HIV-1 Protease Inhibitor: mRNA Display-Derived Hit-to-Lead Optimization.
Release_Year 2022
PMID 36262395
DOI 10.1021/acsmedchemlett.2c00310